Laboratoire d'optique et biosciences
Laboratoire d'optique et biosciences
Laboratoire d'optique et biosciences

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New publication in APL Photonics - Advanced optical polarimetric microscopy reveals spatio-temporal dynamics of cervix remodeling during gestation
09.11.2026
New publication in APL Photonics - Advanced optical polarimetric microscopy reveals spatio-temporal dynamics of cervix remodeling during gestation
Congratulation, a nice study by Laboratoire d'Optique et Biosciences (LOB) colleagues Vaky Abdelsayed, Pierre Mahou, Gaël Latour, Marie-Claire Schanne-Klein and their collaborators in Jessica Ramella-Roman's group at Florida International University. They...
New publication in APL Photonics - Resonant third harmonic generation in biological pigments
08.14.2026
New publication in APL Photonics - Resonant third harmonic generation in biological pigments
A new article in APL Photonics Resonant third harmonic generation in biological pigments Dees et al, APL Photonics 2026 https://pubs.aip.org/aip/app/article/11/8/086116/3401132/Resonant-third… 🔬🌟 Third-harmonic generation...
Congratulations to Robin Kuhner on winning the Jean-Louis Gerondeau–Safran Award!
07.09.2026
Congratulations to Robin Kuhner on winning the Jean-Louis Gerondeau–Safran Award!
Félicitations à Robin Kuhner pour le prix Jean-Louis Gerondeau – Safran ! Congratulations to Kuhner on winning the Jean-Louis Gerondeau–Safran Award! See more information on: https://intranet.polytechnique.fr/fr/actualites/les-projets-holocyte-et…...
The LOB celebrates its 25th year!
06.18.2026
The LOB celebrates its 25th year!
The Laboratory of Optics and Biosciences (LOB), founded in 2001 under the leadership of Jean-Louis Martin, celebrated its 25th anniversary on June 18 at École Polytechnique. To mark the occasion, dozens of former doctoral and postdoctoral students from...
New publication in Optica - Two-photon light-sheet live imaging at kilohertz frame rate using birefringence-based pulse splitting
06.01.2026
New publication in Optica - Two-photon light-sheet live imaging at kilohertz frame rate using birefringence-based pulse splitting
A new paper from the LOB microscopy unit on high-speed multiphoton light-sheet imaging has been published in Optica. We achieved kilohertz frame rates by enhancing the signal-to-photodamage ratio during live imaging. Two-photon light-sheet live imaging at...
New publication in npj Heritage Science, first paper from the LOB on OCT applied to the investigation of cultural heritage artifacts.
03.28.2026
New publication in npj Heritage Science, first paper from the LOB on OCT applied to the investigation of cultural heritage artifacts.
Congratulation to Gael Latour's team. First paper from the LOB on OCT applied to the investigation of cultural heritage artifacts. We show the interest in imaging varnish layers, measuring their thicknesses and following conservation treatments based on...
Inserm CHAIR (tenure track position) opened in the Laboratoire d'Optique et Biosciences
03.27.2026
Inserm CHAIR (tenure track position) opened in the Laboratoire d'Optique et Biosciences
An Inserm CHAIR (tenure track position) has just been opened in the Laboratoire d'Optique et Biosciences ( Inserm U1182) in École Polytechnique / Institut Polytechnique de Paris on “Development of nano-imaging methods for complex patho-physiological...
A new look at the photocycle of a photoenzyme
03.20.2026
A new look at the photocycle of a photoenzyme
A study conducted by teams from LOB, BIAM Cadarache, and I2BC, combining multiple techniques—including ADASOPS multiscale transient infrared absorption spectroscopy—shows that, contrary to previous assumptions, at physiological temperatures, CO₂ is...
HDR Gael Latour
03.18.2026
HDR Gael Latour
Congratulations to Gaël Latour for his bright defense of his Habilitation à Diriger des Recherches (HDR) titled : « Cornée, parchemin, vernis : la microscopie avancée comme outil d'investigation » !
New Prize
03.12.2026
New Prize
A big congratulations to Kate Sorg, third prize IP Paris My Thesis in 180 Seconds She will take part in the regional final of the MT 180 competition, which will take place on April 16, 2026, at La Terrasse in Gif-sur-Yvette. 2026 Winners The jury...
Defects in DNA repair genes drive the emergence of antimicrobial resistance in Mycobacterium tuberculosis
03.04.2026
Defects in DNA repair genes drive the emergence of antimicrobial resistance in Mycobacterium tuberculosis
The growing problem of antibiotic resistance worsens the social and economic burden of tuberculosis (TB) caused by Mycobacterium tuberculosis ( Mtb ). Using large-scale genomic analyses and genome editing, a LOB team has identified associations between...
Beyond the sequence: when DNA structure regulates genes
03.04.2026
Beyond the sequence: when DNA structure regulates genes
Researchers from the Laboratory for Optics and Biosciences participated in a study showing that certain three-dimensional structures of DNA, known as G-quadruplexes, play a key role in regulating gene expression in mammals. This work was published in...