Laboratoire d'optique et biosciences
Laboratoire d'optique et biosciences
Laboratoire d'optique et biosciences

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Beyond the sequence: when DNA structure regulates genes
03.04.2026
Beyond the sequence: when DNA structure regulates genes
Researchers from the Laboratory for Optics and Biosciences participated in a study showing that certain three-dimensional structures of DNA, known as G-quadruplexes, play a key role in regulating gene expression in mammals. This work was published in...
Mapping the structure of human corneas
03.04.2026
Mapping the structure of human corneas
Obtaining precise information on the structure of the cornea is essential to understanding its ability to guarantee high visual acuity. An original approach has been developed combining SHG microscopy and polarimetry to image the lamellar microstructure...
Multiphoton imaging of kidney stones
03.04.2026
Multiphoton imaging of kidney stones
A team from the Laboratory for Optics and Biosciences (LOB) has obtained proof-of-principle for the classification of kidney stones using multi-photon microscopy combined with polarimetry. This optical method, which has been published in the journal ACS...
The high potential of archaea
03.04.2026
The high potential of archaea
Discovered in the late 1970s, archaea are unicellular organisms with characteristics of both bacteria and more complex organisms. Once shunned, advances in molecular biology and genomics have brought them back into the spotlight. Numerous studies are...
Young Lobsters Day
02.19.2026
Young Lobsters Day
Exciting science and discussion during the "Young Lobsters Day" Young Lobsters Day took place Thursday 19th February (full day). Please find the program attached. Presentation format: Postdocs, 3rd-year PhD students, and 2nd-year PhD students Interns and...
New publication in Nucleic Acids Research ”Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life"
02.01.2026
New publication in Nucleic Acids Research ”Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life"
Happy to share latest article on G-quadruplexes in Archaea: "Archaeal G-quadruplexes: a novel model for understanding unusual DNA/RNA structures across the tree of life" published in Nucleic Acids Research Link in comments (paper in free access). We...
Femtosecond spectroscopy and molecular modeling uncover new insights into flavin photochemistry
10.23.2025
Femtosecond spectroscopy and molecular modeling uncover new insights into flavin photochemistry
Researchers from LOB Ecole Polytechnique and CEA Cadarache uncover the ultrafast photooxidation dynamics of the flavin cofactor in the natural photoenzyme - fatty acid photodecarboxylase (FAP). Using femtosecond transient absorption spectroscopy, the team...
Operation Coquelicots at LOB #coquelicots #IWD2025
03.08.2025
Operation Coquelicots at LOB #coquelicots #IWD2025
The LOB enthusiastically supports Operation Coquelicots and is decked out in red to make women scientists visible!
Ministerial visit at LOB
01.24.2025
Ministerial visit at LOB
The Laboratory for Optics and Biosciences was honored by the visit of Mrs Elisabeth Borne (Minister of State, Minister of National Education, Higher Education and Research) and Mr Philippe Baptiste (Minister attached to the Minister of State, Minister of...
The DNA i-motif is thought to be rare in humans
03.13.2024
The DNA i-motif is thought to be rare in humans
An international consortium of researchers from the Czech Republic, Slovakia, Slovenia, Canada, Spain, Italy and France (at École polytechnique / LOB ) has been investigating the long-standing question of the stability of the unusual "i-motif" nucleic...